Congrats on the new gecko. Most people, I believe, agree that 1-2 weeks is a good amount of time to allow a leopard gecko to settle in before attempting to handle. If I am wrong I'm sure someone will correct me. Also, it is important to remember that leopard geckos are individuals, and it may take longer for some to settle in than others. Just remember, if you try too persistantly to handle a leo that is stressed, it can cause problems like dropping the tail or not eating. If you have not read the care sheets available on this site, I suggest you do so. They will fill you in on things such as temperature, feeding, substrate etc. and may even cover the settling in issue.